| Ciro Tetta, MD Director Extracorporeal Therapies Research Department Bad Homburg, Germany Date of Birth: April 27, 1952.
Place of Birth: Turin (Italy).
Marital Status: married, 1 daughter, 1 son.
Citizenship: Italian
Permanent Address: Via dei Mille, 23 - Mirandola
Work Address: Fresenius Medical Care
DeutschlandGmbH
R & D International
DaimlerStrasse 15,
61352 Bad Homburg - Germany
Portable phone number ++39 335 7869152
Work telephone number: ++49 6172 6092417
E-mail (personal): cirotetta@hotmail.com
E-mail (work): Ciro.Tetta@fmc-ag.com
Appointments:
2002-to present Director, Research Extracorporeal Therapies, Division of Medicine, Fresenius Medical Care, Bad Homburg, Germany
2002-to-present Contract Professor of Nephrology, School of Nephrology, University of Turin, Turin, Italy
2002-to-present Contract Professor of Nephrology, School of Nephrology, University of Modena, Modena, Italy
2001-to present Professor, School of Nephrology, University of Turin, Turin, Italy
1991-2002: Head, Clinical and Laboratory Research Department at Bellco, Bellco SpA (Mirandola, I).
1989-1991: Clinical Research Associate, Dialysis & Tranplantation Unit, St.John's Hospital, Turin.
1982-1989: Research Associate, Laboratory of Immunopathology, University of Turin.
1980-1982: Clinical Research Associate, Rheumatology Unit, St. John's Hospital, Turin, Italy.
1978-1980: Specialty in Nephrology, University of Turin (School of Nephrology, Dialysis and Transplantation).
1971-1977: University of Turin, Turin (Italy) (Medical degree).
Accademic appointments:
Contract Professor of Nephrology, Biotechnology Postgraduate Course, University of Turin (1998 to present )
Professor of Nephrology, School of Nephrology, University of Modena (2002 to present)
Contract Professor of Immunonephrology, School of Nephrology, University of Reggio Calabria (1989-1995).
Contract Professor of Immunology, School of Nephrology, University of Turin, (1988-1991).
Medical appointments:
Clinical Research Associate, Chair of Nephrology and Department of Nephrology, Dialysis and Transplantation (1977-1991).
Present appointment: Director, Extracorporeal Therapies Research, Division of Medicine, Fresenius Medical Care, Bad Homburg, Germany.
Main areas of research: Biocompatibility, "hemodialysis", dialysis modalities, bio-sensing in hemodialysis, extracorporeal treatments in acute renal failure, sepsis and septic shock, liver transplantation
Memberships: AAAS, ASAIO, ASN, EDTA, ESAO (also Member of the Editorial Board of the ESAO Journal), ISAO, ISBP, ISPD, ISN, NKF, SIN, IES,
Pubblications (1977- ): 235 original papers; 96 chapters on books or editorials; 51 invited lectures, 175 oral or poster communications.
Patents: Inventor, #99109637. 1-2305: “Method for ectracorporeal removal of toxins, in particular cytokines, particularly for treating patients affected with acute organ failure”.
Inventor, #99111638.5-2305: “Method of rapidly removing liposoluble target molecules from a colloidal solution and wash solution for such a method”.
Grants: Project no 527: “New methods in the extracorporeal treatment of sespis and septic shock”, financed by the Italian Ministry of the University, 1996-2000.
BRITE-EURAM Project “Nanotechnology and Medicine (NANOMED)”
Project: “Targeting and imaging of solid tumors: application of extracorporeal therapies”, MIUR (Ministero dell’Universita’ e della Ricerca), submitted October 2001, 4.5 milion Euros
Stages 1992: CHU Lapeyronie, Montpellier (Fr): Developement of a new on-line urea sensor. Mentors: Prof Charles Mion, Prof. Bernard Canaud.
1994: Medizine Hochschule Hannover (De): Development of new sorbents for the extracorporeal treatment of sepsis and septic shock. Mentors: Prof. Karl Koch, Dr Gerhard Lonnemann.
1995: Hospital Universitario Gregorio Maranon, Madrid (E): Cytokine profiling in high flux hemodialysis. Mentors: Prof. Fernando Valderrabano, Dr Raphael Perez.
1996: CHU Hopital Eduard Herriot, Lyon (Fr): Markers of chronic inflammation in hemodialysis patients. Mentors: Prof. Maurice Laville, Prof. Denis Fouque.
2001: University Hospital of Parma, Parma (I): Biologic and clinical effects of hemoconcentration. Mentors: Prof. Vincenzo Cambi, Prof Salvatore David.
2002: St Bortolo Hospital, Vicenza (I): Machines, dialyzers and techniques for innovative strategies in the critically ill patient. Mentors: Prof. Giuseppe La Greca, Dr Claudio Ronco.
· Equipment and technical experience: cell cultures, immunological techniques (immunofluorescence, FACS, affinity chromatography), protein purification methods, endotoxin purification and characterization, blood-material interaction (purification and characterization of lipid inflammatory mediators), immobilization of proteins on matrices.
· Cell biology and signal transduction in apoptosis.
· Methodology for investigating hyporesponsivess in sepsis.
· Laboratory and Clinical protocols: sperimentation of unregistered medical devices (EN 540). Phase I and II clinical trials.
· Dialyzers (new membranes)
· Hemodialysis techniques (HFR, CPFA, PHF, Hemolipodialysis)
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