Search © 2013 CRRT Inc. AKI& CRRT 2015 Conference - Program and Workshops Complete CRRT Brochure PDF (988K) Monday, February 16 5:00-8:00pm Conference Registration Open Tuesday, February 17 Pre-Conference AKI Symposium 7:00am Conference and Workshop Registration Open 8:00-5:30 PW1 Changing Paradigms in Acute Kidney Injury: From Mechanisms to Management sponsored by: The UAB-UCSD O'Brien Core Center for Kidney Injury Research Acute Kidney Injury is a rapidly evolving area where several advances have been made in understanding the mechanisms and pathways of AKI and its effects on other organs. Recent identification of biomarkers has provided new tools and techniques to characterize this disorder. This pre-course workshop will provide a comprehensive review of the most recent developments in the field and describe emerging knowledge from basic and translational research. Results from clinical trials will be discussed to define the best strategies for effective management of patients and define the criteria for future studies. CRRT Conference registration is not required to attend this symposium, separate registration is available. 7:55-8:00 PW1 Opening Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP, AKI Symposium - Plenary 1 Molecules, Mechanisms and Targets 8:00-10:00 Co-chair: Anupam Agarwal, MD Co-chair: Bruce A. Molitoris, MD 8:00-8:20 PW1 The Yin and Yang of AKI: Bioenergetic Failure or Conservations Hernando Gomez, MD, MPH 8:20-8:40 PW1 Ferritin in AKI Subhashini Bolisetty, PhD 8:40-9:00 PW1 Renal Oxygenation and Mitochondrial Function in Sepsis-Associated AKI Prabhleen Singh, MD 9:00-9:20 PW1 Neuro Immune Control of AKI and Inflammation Mark D. Okusa, MD 9:20-9:40 PW1 Gene Discovery for Different Subsets of AKI Jonathan Barasch, MD PhD 9:40-10:00 PW1 Discussion 10:00-10:15 Coffee Break AKI Symposium - Plenary 2 Harmonizing Human and Animal AKI: Results from ADQI 13 10:15-12:15 Co-chair: Mark D. Okusa, MD Co-chair: Mitchell H. Rosner, MD 10:15-10:35 PW1 Hemodynamics Can Ince, PhD 10:35-10:55 PW1 Immunity, Inflammation Sunderaraman Swaminathan, MD 10:55-11:15 PW1 Cellular and Molecular Anupam Agarwal, MD 11:15-11:35 PW1 Progression David Basile, Ph.D 11:35-11:55 PW1 Regeneration and Stem Cells? Christof Westenfelder, MD 11:55-12:15 PW1 Discussion 12:15-1:15 Lunch Hosted by Conference for Workshop Participants AKI Symposium - Plenary 3 Bench to Bedside: Translating Discoveries to Clinical Care 1:15-3:15 Co-chair: Paul Palevsky, MD Co-chair: Didier Payen, MD 1:15-1:35 PW1 Parenteral Angiotension II for Shock: Effects on Renal Function Lakhmir S. Chawla, MD 1:35-1:55 PW1 Electrical Vagal Nerve Stimulation in Humans: Effects on the Immune Response Peter Pickkers, MD, PhD 1:55-2:15 PW1 Genomic and Proteomic Characterization of AKI Prasad Devarajan, MD 2:15-2:35 PW1 Detecting Drug Nephrotoxicity: The Kidney on a Chip Vishal Vaidya, PhD 2:35-2:55 PW1 Urine Exosomes and Molecular Characterization of AKI Satish Rao, PhD 2:55-3:15 PW1 Discussion 3:15-3:30 Coffee Break AKI Symposium - Plenary 4 Controversies in AKI 3:30-5:30 Co-chair: Patrick T. Murray, MD Co-chair: Claudio Ronco, MD 3:30-3:50 PW1 Timely Diagnosis of AKI: Kinetic eGFR - Creatinine Can be Useful Zoltan Endre, MD, PhD 3:50-4:10 PW1 Pathogenesis of AKI the Problem is Right Under Our Nose John A. Kellum, MD 4:10-4:30 PW1 How Should We Quantify the Effect of AKI on CKD Paul Kimmel 4:30-4:50 PW1 Long Term Outcomes from AKI; Lessons from the ARID Study Nick Selby, MD 4:50-5:10 PW1 Can We Personalize RRT Based Biomarker Profiles? Raghavan Murugan, MD, MS, FRCP 5:10-5:30 PW1 Discussion 5:30pm AKI Symposium Adjourns Tuesday, February 17 Practice Based Learning in CRRT: The Science and the Art PW2 - Practice Based Learning in CRRT: The Science and the Art This workshop is designed to provide participants with the knowledge and understanding for decision making for the effective utilization of CRRT to manage critically ill patients. The workshop will utilize case based discussions to illustrate the underlying concepts for application of CRRT. All participants will be provided access to digital media describing the basic concepts of CRRT and will be expected to have reviewed this material prior to the workshop. Delegates will participate in group exercises to apply their learning for the management of complex cases. At the end of this workshop participants will have an improved understanding of how to utilize CRRT for optimizing renal support. A quiz will be administered pre-and post- course for assessment. The participants will be divided into two teams, one led by Dr. Tolwani and one led by Dr. Cerda. The participants will go through three interactive case simulations and role-playing with their assigned team in the morning and then will switch to the other team in the afternoon. This allows all participants to participate in each physician-led group and go through a total of 6 scenarios covering all aspects of CRRT. Full Day Concurrent Elective Workshop - PW2 8:00-5:00 Co-chair: Jorge Cerda, MD, FACP, FASN Co-chair: Ashita Tolwani, MD 7:50-8:00 PW2 Opening Remarks Jorge Cerda, MD, FACP, FASN Ashita Tolwani, MD 8:00-8:45 PW2 Pre-Course Test Jorge Cerda, MD, FACP, FASN Michael Connor, MD Ashita Tolwani, MD 8:45-9:25 PW2 Nurses Breakout Session: Machine Setup, Alarms, and Trouble-shooting Patty Graham, RN, MS, CCRN, CS Catherine Wells, DNP, ACNP-BC, CNN-NP 8:45-9:25 PW2 Physicians Breakout Session: CRRT Prescription, Order Sets, and Fluid Composition Linda Awdishu, PharmD, MAS Jorge Cerda, MD, FACP, FASN 9:25-1:00 PW2 Hands-On Simulation Workshop Rotations - All Teams 9:25-1:00 PW2 Session 1 Anticoagulation, Citrate Protocols Teri Shell, RN Ashita Tolwani, MD Catherine Wells, DNP, ACNP-BC, CNN-NP Circuit setup, anticoagulation, modalities 9:25-1:00 PW2 Session 2 Dose/Fluid/Documentation Jorge Cerda, MD, FACP, FASN Patty Graham, RN, MS, CCRN, CS Luis Juncos, MD Mary Marshall, RN Solutions, volume management, electrolytes, acid base; divalent ions, fluid adjustments, dose 9:25-1:00 PW2 Session 3 Decision Making and Coordination of Care Linda Awdishu, PharmD, MAS Michael Connor, MD Dinna Cruz, MD, MPH Sequential adjustments coordinating operational characteristics to adjust dose, deal with plasma compositions fluid balance, drug dosing 9:25-1:00 PW2 Session 4 Pediatric/ECMO/Hybrid David Askenazi, MD Stuart L. Goldstein, MD Modality selection, circuit modifications, therapy dosing, monitoring, adjustments for targeted interventions 1:00-1:45 Lunch Hosted by Conference for Workshop Participants 1:45-4:25 Interactive Case-based Scenarios (All teams together in lecture room with audience response system) 1:45-2:10 PW2 Nutrition Michael Connor, MD 2:10-2:23 PW2 Drug Dosing for CRRT Linda Awdishu, PharmD, MAS 2:35-3:00 PW2 Discontinuation of CRRT and/or Transition to Other Dialytic Modalities Dinna Cruz, MD, MPH 3:00-3:25 PW2 Ethical Considerations Jorge Cerda, MD, FACP, FASN Stuart L. Goldstein, MD 3:25-3:40 Coffee Break 3:40-4:25 PW2 Interactive Video Simulation: Real-time, Case Based Scenario from Consent to Delivery Ashita Tolwani, MD 4:25-5:00 PW2 Post Course Test and Wrap-up Jorge Cerda, MD, FACP, FASN Michael Connor, MD Ashita Tolwani, MD 5:00pm PW2 Adjourn Tuesday, February 17 Peritoneal Dialysis for AKI PW3: Peritoneal Dialysis for AKI Peritoneal dialysis (PD) is often overlooked as a therapeutic option for managing hospitalized patients with AKI as there is lack of experience with this technique. Recent studies have shown that this is a complementary therapy to CRRT and IHD techniques for both the primary treatment of AKI from its onset to recovery and as a transition of care from the ICU to post-ICU setting to support organ systems and enhance recovery of kidney function. Additionally, PD has been effectively utilized to manage patients with chronic heart failure, liver failure and patients with brain edema. PD has been the mainstay of therapy for AKI in several countries where IHD and CRRT are not available or economically feasible. This workshop provides physicians and nurses with the background knowledge, skills, and hands-on training to utilize peritoneal dialysis (PD) for the management of patients with acute kidney injury. The workshop will cover the principles of PD, demonstrate the practical considerations for obtaining PD access, setting up and operating manual and cycler based treatment regimens and techniques for monitoring and management of complications. Full Day Concurrent Elective Workshop - PW3 8:00-5:15 8:00-10:00 PW3 SESSION 1: Principles and Practice of PD in the Hospitalized Patient Fred Finkelstein, MD Daniela Ponce, MD • Anatomy and Physiology of the Peritoneum • Physiologic Principles and Targets for PD Adequacy and Ultrafiltration • Operational Characteristics: Catheter placement, Access, Solutions, Orders, Cycler, Connectology 10:00-10:15 Coffee Break 10:15-12:15 PW3 SESSION 2: Practical Issues for PD in AKI Fred Finkelstein, MD Daniela Ponce, MD • Rationale for Use of PD in AKI: Initial Therapy, Transition Therapy In-hospital and at Discharge • Nursing Issues: Set-up, Monitoring, PD Volume Adjustments, Assessing for Complications, Charting and Recording, Patient Training and Ancillary Staff Education • Management of Infections (Management of Peritonitis, ESI) and Catheter Problems 12:15-1:15 Lunch Hosted by Conference for Workshop Participants 1:15-3:00 PW3 SESSION 3: Setting Up and Maintaining and Acute PD Program Steven R. Alexander, MD Fred Finkelstein, MD Daniela Ponce, MD • Administrative Issues, Quality Measures • Special Topics: Pediatric Issues, Heart Failure, Liver Failure with Ascites, Brain Edema, Transitioning to IHD or CRRT • Interactive Case Scenarios for Management Decisions (Drug Dosing, Nutritional Support) 3:00-3:15 Coffee Break 3:15-5:15 PW3 SESSION 4: Hands-on Demos Catheter Placement with Mannequins - Physicians Cycler Set-up and Troubleshooting - Nurses Sean Armstrong, MD Todd Penner, MD Daniela Ponce, MD • Peritoneal Dialysis Catheter Placement and Management (3 stations and cycler set-up at 2 stations) 5:15 PW3 Adjourn 6:00-7:30pm Reception and Poster Review For All Conference Attendees Wednesday Morning, February 18 STANDARD WORKSHOPS Open to all participants and applicable to physicians, nurses and allied personnel. Workshop Codes: C= Core workshop, I = Intermediate, A = Advanced, N= Nurses, AP = of interest to Nurses and Allied Personnel Workshops presented in a series are marked with a ''1'' for a primary workshop discussion in this area and ''2'' for a more complex or advanced discussion in this area. Please note that the series workshops 1 and 2 can be either taken subsequently (following each other) or they can each be taken independently (e.g. workshop 1 can be taken without taking workshop 2 and vice versa). 7:00-4:30pm Conference Registration Open 7:15-8:15 ME1 MEET THE EXPERT How do I Manage Patients with High Risk for AKI in the ICU Kianoush Kashani, MD Miet Schetz, MD, PhD 7:15-8:15 ME2 MEET THE EXPERT How do I Assess and Follow Up Patients After an Episode of AKI Paul Palevsky, MD Nick Selby, MD Standard Workshop Group 1 8:30-10:00 8:30-10:00 A01 Using Kidney Biomarkers for AKI 1: Risk Assessment, Diagnosis and Staging (C,N,AP) Rajit Basu, MD Kent Doi, MD Patrick T. Murray, MD Practical issues for use of kidney biomarkers for assessing risk and for early recognition and interventions in AKI. 8:30-10:00 B02 Strategies for Optimizing the CRRT Circuit (Access, Anticoagulation and Monitoring) Citrate Anticoagulation (C,N,AP) David Askenazi, MD Achim Jorres, MD Luis Juncos, MD Case based discussions on best practices to maintain circuits for CRRT focusing on the Access, Anticoagulation and Monitoring. Citrate anticoagulation 8:30-10:00 C03 Vexing Problems in ICU Patients 1: Acid Base and Electrolyte, Sedation, Resistant Infections, C-diff, the Obese Patient (C,N,AP) Noel Gibney, MB FRCP(C) Marlies Ostermann, MD Mitchell H. Rosner, MD Test and update your knowledge with these interactive case studies focused on recognizing and managing acid base and electrolyte problems in critically ill patients. 8:30-10:00 D04 Managing Patients with AKI and Liver Failure 1: Pathophysiology, Differential Diagnosis, Therapy, Use of RRT, Liver Support, Strategies for Bridge to Transplant (C,N,AP) Andrew Davenport, MD, FRCP Heather Patton, MD Pathophysiology of AKI in setting of acute and chronic hepatic failure and management strategies for differential diagnosis and therapy. 8:30-10:00 E05 Assessment of Fluid Responsiveness, Hemodynamic Monitoring and Targets (C, N) Can Ince, PhD Kianoush Kashani, MD Peter Pickkers, MD, PhD Principles and strategies for volume assessment, hemodynamic and microcirculatory monitoring in critically ill patients. 8:30-10:00 F06 Ensuring Patient Safety and Quality for RRT in AKI (C,N,AP) Saima Aslam, MD Thomas A. Golper, MD Ron Wald, MD Water Standards, Infection Control, Regulatory issues, Dialysis Adequacy, Monitoring, Benchmarks for Quality assessment. 8:30-10:00 G07 Principles of Plasma Exchange, Applications and Practical Issues (C,N,AP) Eisei Noiri, MD, PhD David M. Ward, MD, FRCP Rationale and technique of plasma exchange and its applications, case based discussions. 10:00-10:15 Coffee Break Standard Workshop Group 2 10:15-11:45 10:15-11:45 A08 Using Kidney Biomarkers for AKI 2: Differential Diagnosis, Interventions and Prognosis (C,N,AP) Zoltan Endre, MD, PhD Stuart L. Goldstein, MD Jay Koyner, MD Strategies for the effective use of kidney biomarkers for managing patients with AKI to guide interventions and predict outcomes. 10:15-11:45 B09 CRRT for the Experienced User 1 (I,N,AP) Rolando Claure, MD, FASN Claudio Ronco, MD Interactive case based discussions on dose adjustments, monitoring for adequacy, modality selection and transitions in CRRT. 10:15-11:45 C10 Starting and Stopping RRT for AKI: Principles and Practice (A) Etienne Macedo, MD, PhD Ravindra L. Mehta, MBBS, MD, DM, FACP, Principles of determining when to start and stop RRT. Case based discussion of various approaches. 10:15-11:45 D11 Managing Patients with Sepsis 1 : Pathophysiology, Diagnosis, Assessment, Resuscitation, Drug Management, Techniques for Disease Modification, Organ Support and Renal Protection (C,N,AP) Geoffrey Fleming, MD Patrick M. Honoré, MD, PhD Achim Jorres, MD Case based discussions on pathophysiology of sepsis, rationale and strategies for fluid and vasopressor use for supportive therapy with the sepsis bundle. Technical considerations and practical application of extracorporeal support techniques for sepsis. Results of human studies for use of high permeability membranes, HVHF, VHVHF and hybrid techniques for sepsis. 10:15-11:45 E12 Fluids and Solutions Crystalloids, Colloids and Blood Products: When and How to Use (I,N,AP) Lakhmir S. Chawla, MD Oliver Joannes-Boyau, MD John A. Kellum, MD Techniques, applications, monitoring and practical issues for implementation. 10:15-11:45 F13 Pediatric Dialysis Techniques 1: Patient Assessment, Prescription, Dosing, Delivery, Implementation and Monitoring (I,N,AP) Theresa Mottes, RN Scott Sutherland, MD Jordan M. Symons, MD Technique requirement and application for use in children excluding neonates. Covering epidemiology ofpediatric AKI, and a focus on the pediatric CRRT prescription (anticoagulation, fluid composition, modality, and nutrition provision), as well as outcomes. 10:15-11:45 G14 Practical Issues in Plasmapheresis: Setup and Troubleshooting, Combined CRRT with Pheresis (C,N) Isagani Marquez Noel Oabel, BSN RN CNN David M. Ward, MD, FRCP Technique adaptations for combining CRRT with other extracorporeal support therapies. Circuit set up, logistics, monitoring and assuring safety. 11:45-1:00 Lunch Symposia Hosted by Conference (RSVP Required) Selection made during registration Luncheons 11:45-1:00 Fluid Management of the Critically Ill Patient: When, How Much and What? Daniel De Backer, MD Didier Payen, MD John Prowle, MA MSc MD MRCP FFICM Co-Chairs: Peter Pickkers, MD & Claudio Ronco, MD CME Available This symposium will discuss the pathophysiology for fluid distribution, review recent evidence for the optimal application of fluids to support ICU patients safely in the ICU. 11:45-1:00 Quality Metrics for AKI and RRT: Should We Have Benchmarks? Nick Selby, MD Ron Wald, MD Co-Chairs: Nick Selby, MD & Ron Wald, MD CME Available There is a major imperative to focus our efforts on developing clinical quality measures (CQMs) to track and report on care for AKI patients and identify best practices to improve outcomes. This symposium will describe the key issues that need to be considered to establish performance measures for AKI. 11:45-1:00 Spectral Medical Inc. Luncheon Endotoxin Removal: The Time is Here Non-CME This interactive session will focus on the topic of endotoxin removal with the PMX cartridge. It will include a presentation of up to date evidence collected from European clinical trials, International Registries and a Japanese National Diagnostic Code 4 year review. A comparative grid of the features, benefits and risks of the polymyxin B (PMX) cartridge versus other anti-endotoxin membranes. Finally an update on the EUPHRATES trial will be presented. Wednesday Afternoon, February 18 Opening Session SESSION I: PATIENT CHARACTERISTICS Plenary 1 MINI-SYMPOSIA Organ Dysfunction in the Critically Ill Patient: Emerging Concepts 1:10-3:45 Co-chair: Lakhmir S. Chawla, MD Co-chair: Mark D. Okusa, MD 1:10-1:15 Opening Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP, 1:15-1:30 Hypoxia and inflammation: Lessons for Critical Illness Peter Pickkers, MD, PhD 1:30-1:45 Immunodepression: A Real Clinical Entity in ICU Patients Didier Payen, MD 1:45-2:00 The Microcirculation in Sepsis: Target for Intervention? Daniel De Backer, MD 2:00-2:15 Endothelial Hyperpermeability in Critical Care and Its Countermeasures with CHDF Hiroyuki Hirasawa, MD, PhD 2:15-2:30 Pathophysiology of Kidney Dysfunction in Liver Disease Andrew Davenport, MD, FRCP 2:30-2:45 Intraabdominal Hypertension: The Enemy Within Atul Malhotra, MD 2:45-3:10 SPECIAL LECTURE The EBOLA Epidemic: Lessons Learned and Applied Michael Connor, MD 3:10-3:30 Panel Discussion 3:30-4:00 Coffee Break Plenary 2 MINI-SYMPOSIA Acute Kidney Injury (AKI): Pathophysiology 4:00-6:00 Co-chair: Zoltan Endre, MD, PhD Co-chair: Luis Juncos, MD Co-chair: Paul Sanders, MD 4:00-4:15 Renal Reserve: Can We Assess It? Claudio Ronco, MD 4:15-4:30 Measuring GFR in the ICU: Which technique and Which GFR? Bruce A. Molitoris, MD 4:30-4:45 HMGB1-TLR4 Interactions: Mediators of Kidney Lung Cross Talk? Kent Doi, MD 4:45-5:00 Immunoregulatory Role of Tissue Microenironment in Kidney Injury Mark D. Okusa, MD 5:00-5:15 Preeclampsia: Pathophysiology and Management Douglas Woelkers, MD 5:15-5:30 MicroRNA Profiling: Insights into AKI Vishal Vaidya, PhD 5:30-5:50 Biomarkers for Drug Nephrotoxicity Patrick T. Murray, MD 5:50-6:00 Panel Discussion 6:00 Adjourn 6:00-8:00 Exhibit Reception and Poster Session Thursday Morning, February 19 7:00am-4:30pm Registration Open 7:00-8:00 Coffee Served 7:15-8:15 ME3 MEET THE EXPERT How I Assess Patients in the ICU and My Approach to Oliguria Daniel De Backer, MD Peter Pickkers, MD, PhD 7:15-8:15 ME4 MEET THE EXPERT How I Use the KDIGO AKI Guidelines to Manage Patients John A. Kellum, MD Claudio Ronco, MD Standard Workshop Group 3 8:15-9:45 8:15-9:45 A15 Optimal Care for AKI: The 5 R Approach (C,N,AP) Steven R. Alexander, MD Jorge Cerda, MD, FACP, FASN Andrew Lewington, MD This workshop will describe the urgent need for educating care givers, patients and the lay public on the devastating effects of AKI. Strategies and tools for risk assessment, recognition response, rehabilitation and referral for AKI will be discussed. 8:15-9:45 B16 CRRT for the Experienced User 2: Solutions, Fluid Removal Fluid Balance, Monitoring (A) Ravindra L. Mehta, MBBS, MD, DM, FACP, John Prowle, MA MSc MD MRCP FFICM Interactive case based discussion on strategies for fluid management in CRRT to achieve patient driven outcomes for fluid, electrolyte and acid base balance. 8:15-9:45 C17 Drug Induced Kidney Injury in the ICU: Mechanisms, Susceptibility, Diagnosis, Management Strategies (A,N) Linda Awdishu, PharmD, MAS Oliver Joannes-Boyau, MD Scott Sutherland, MD Causes and consequences of drug induced nephrotoxicity, factors contributing to toxicity, strategies for preventing and managing toxicity. Utilization of dialysis techniques for drug removal. 8:15-9:45 D18 Managing Heart Failure and Cardio-Renal Syndrome: Pathophysiology, Diagnosis, Drug Management, Ultrafiltration, Renal Support and RRT for Patients with Ventricular Assist Devices and Artificial Hearts (A,N) Luis Juncos, MD James A. Tumlin, MD Technical considerations, practical application and results of different methods to treat heart failure and cardio-renal syndrome including ultrafiltration techniques. 8:15-9:45 E19 Vasopressors and Inotropes and Combinations with Fluid (I,N) Daniel De Backer, MD Raghavan Murugan, MD, MS, FRCP Miet Schetz, MD, PhD Pathophysiology of shock and the principles and practical use of vasopressors, inotropes, vasodilators in critically ill patients. 8:15-9:45 F20 Pediatric Dialysis Techniques 2: CRRT in the Newborn; ECMO and Combination Therapies (C,N,AP) Amelia Allsteadt, BSN,RN,CNN David Askenazi, MD Geoffrey Fleming, MD Discussion of the principles of a systems based approach to implementing and monitoring quality to reduce errors in therapy prescription and delivery. 8:15-9:45 G21 Sorbent Based and Hybrid Therapies for Extracorporeal Support (I,N,AP) Dinna Cruz, MD, MPH Hiroyuki Hirasawa, MD, PhD Achim Jorres, MD Hemopurification systems for sepsis, immunoadsoprtion and PMMA. 9:45-10:00 Coffee Break SESSION II: CONTROVERSIES IN CRITICAL CARE NEPHROLOGY Plenary 3 MINI-SYMPOSIA Challenges in ICU Management 10:00-12:15 Co-chair: Paul Palevsky, MD Co-chair: Didier Payen, MD 10:00-10:15 Vancomycin Nephrotoxicity: A Figment of Imagination Saima Aslam, MD 10:15-10:30 Sedation and the Kidney: Cause for Concern? Peter Pickkers, MD, PhD 10:30-10:45 End Stage Liver Disease in the ICU: Should we offer RRT? Andrew Davenport, MD, FRCP 10:45-11:00 Progressive Mobility and the Criticaly Ill Patient Patty Graham, RN, MS, CCRN, CS 11:00-11:15 Microcirculation Targeted Fluid Management Daniel De Backer, MD 11:15-11:30 EGDT Doesn't Help the Kidney Either John A. Kellum, MD 11:30-12:00 SPECIAL LECTURE Three Decades of CRRT: The Past the Present and the Future Claudio Ronco, MD 12:00-12:15 Top Abstract Awards 12:15-1:45 Lunch Symposia Hosted by Conference (RSVP Required) Selection made during registration Luncheons 12:15-1:45 Improving Outcomes in AKI: How do Biomarkers Fit In? Jay Koyner, MD Patrick T. Murray, MD Alex Zarbock, MD Co-Chairs: John Kellum, MD & Kianoush Kashani, MD CME Available Several novel biomarkers for AKI are now available for clinical use, however experience has been limited. This symposium will provide a review of the field and discuss how these biomarkers are being used to optimize patient management. 12:15-1:45 Managing Hyperkalemia in AKI and CKD: A Shifting Paradigm Mitchell H. Rosner, MD Bruce Spinowitz, MD Co-Chairs: James Tumlin, MD & Tom Golper, MD CME Available Potassium derangements are common in patients with reduced kidney function and often result in life threatening events requiring emergent use of RRT. The development of hyperkalemia also prompts stopping drugs that are beneficial but pose a high risk. This symposium will discuss the benefits and limitations of current treatment strategies and describe the efficacy of a novel therapy for managing acute and chronic hyperkalemia. 12:15-1:45 Alexion Pharmaceuticals Luncheon Advances in the Understanding of aHUS Non-CME This presentation is given by Arif Asif, MD, Professor of Medicine and Chief of Nephrology and Hypertension at Albany Medical College. SESSION III: EMERGING CONCEPTS IN AKI AND RRT Plenary 4 MINI SYMPOSIA Novel Strategies in AKI Management 1:45-3:30 Co-chair: Stuart L. Goldstein, MD 1:45-2:00 Assessing Renal Recovery: Estimated vs Measured GFR Miet Schetz, MD, PhD 2:00-2:15 Combining Functional and Structural Biomarkers to Assess AKI Rajit Basu, MD 2:15-2:30 Acute on Chronic Kidney Disease: Changes in Biomarker Profiles Zoltan Endre, MD, PhD 2:30-2:45 HUS-TTP: Everything has Changed in the Last Ten Years But Still a Lot to Do Giuseppe Remuzzi, MD 2:45-3:00 Targeting Renal Recovery from AKI: The Role of Anemia Ravindra L. Mehta, MBBS, MD, DM, FACP, 3:00-3:15 Drug Interactions: The Hidden Risk for AKI Ron Wald, MD 3:15-3:30 AKI as a Quality Paradigm: Report from the Roundtable Conference Sean Bagshaw, MD, MSc, FRCPC 3:30-4:00 Coffee Break Plenary 5 MINI SYMPOSIA Challenges and Controversies in Renal Support and CRRT 4:00-6:00 Co-chair: Dinna Cruz, MD, MPH Co-chair: Miet Schetz, MD, PhD 4:00-4:15 Optimizing RRT for AKI Andrew Davenport, MD, FRCP 4:15-4:30 Apheresis Techniques: Applications for Renal Support David M. Ward, MD, FRCP 4:30-4:45 Advanced CRRT Techniques: Combining CRRT with ...ECMO, MARS and Plasmapheresis David Askenazi, MD 4:45-5:00 Automated Citrate Anticoagulation for CRRT Marlies Ostermann, MD 5:00-5:15 Peritoneal Dialysis: An Alternate CRRT for AKI? Daniela Ponce, MD 5:15-5:30 Managing Acid Base and Electrolyte Disturbances with RRT John Prowle, MA MSc MD MRCP FFICM 5:30-6:00 DEBATE Hemofiltration for Sepsis: Burial or Resurrection? Patrick M. Honoré, MD, PhD Didier Payen, MD Claudio Ronco, MD Pro: Honore Con: Payen Moderator: Ronco 6:00 Adjourn Free Evening Friday Morning, February 20 7:00-1:00 Conference Registration Open 7:30-8:00 Coffee Served SESSION IV: IMPROVING OUTCOMES IN AKI Plenary 6 MINI SYMPOSIA Raising Awareness of AKI - The ISN 0by25 Initiative 8:00-10:15 Co-chair: Steven R. Alexander, MD Co-chair: Andrew Davenport, MD, FRCP 8:00-8:15 AKI 0by25: A Call for Action Giuseppe Remuzzi, MD 8:15-8:30 Design and Conduct of AKI 0by25 Initiative Ravindra L. Mehta, MBBS, MD, DM, FACP, 8:30-8:45 Global Epidemiology of AKI: What Have We Learnt? Jorge Cerda, MD, FACP, FASN 8:45-9:00 How Does AKI Contribute to the Global Burden of Disease Bernadette Thomas, MD, MS 9:00-9:15 Tools to Raise Awareness of AKI: A Global Need Andrew Lewington, MD 9:15-9:30 Providing Dialysis Support for AKI in the Developing World: The Role of PD Fred Finkelstein, MD 9:30-9:45 Assessment of Worldwide AKI, Renal Angina and Epidemiology in Children: The International AWARE Study Stuart L. Goldstein, MD 9:45-10:15 The Changing Face of AKI: Snapshots from Around the World India, Latin America Sanjay Agarwal, MD Emmanuel Burdmann, MD, PhD 10:15-10:45 Coffee Break SESSION V: FUTURE TRENDS IN CRRT AND CRITICAL CARE Plenary 7 MINI SYMPOSIA Emerging Strategies in AKI and Extracorporeal Support 10:45-1:00 Co-chair: Kianoush Kashani, MD Co-chair: Andrew Lewington, MD 10:45-12:30 Update from Ongoing and Late Breaking Trials (12 minutes each) Sean Bagshaw, MD, MSc, FRCPC Hiroyuki Hirasawa, MD, PhD Achim Jorres, MD Samina Khan, MD David Klein, MD MDA Bruce Spinowitz, MD James A. Tumlin, MD Alex Zarbock, MD 1. Frequency and Distribution of Dialysis-Associated Atrial Fibrillation: Preliminary Results of the Monitoring in Dialysis (MiD) Study (Tumlin) 2. STARRT Trial Timing of Dialysis (Bagshaw) 3. ZS Pharma HARMONIZE Trial for hyperkalemia (Spinowitz) 4. Polymixin Binding Filter for Sepsis: EUPHRATES Trial (Klein) 5. CONVINT Trial (Jorres) 6. Remote Ischemic Preconditioning to Prevent AKI in Cardiac Surgery Patients (Zarbock) 7. sepXiris - A New Cytokine-Adsorbing Hemofilter for Sepsis ((Hirasawa) 8. Prevention of AKI in Patients Undergoing Cardiac Surgery: Results from M13-796 Trial (Khan) 12:30-12:55 Critical Care Nephrology: Literature Review Noel Gibney, MB FRCP(C) 12:55-1:00 Closing Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP, 1:00 Conference Adjourns