Search © 2017 CRRT Inc. AKI & CRRT 2017 Conference - Program and Workshops Monday, March 6 4:00-7:00pm Conference Registration Open Pre-Conference AKI Symposium Tuesday, March 7 7:00am Conference and Workshop Registration Open 7:55-5:30 7:55-5:30 PW1 Changing Paradigms in Acute Kidney Injury: From Mechanisms to Management sponsored by: The UAB-UCSD O'Brien Core Center for Kidney Injury Research Acute Kidney Injury is a rapidly evolving area where several advances have been made in understanding the mechanisms and pathways of AKI and its effects on other organs. Recent identification of biomarkers has provided new tools and techniques to characterize this disorder. This pre-course workshop will provide a comprehensive review of the most recent developments in the field and describe emerging knowledge from basic and translational research. Results from clinical trials will be discussed to define the best strategies for effective management of patients and define the criteria for future studies. CRRT Conference registration is not required to attend this symposium, separate registration is available. 7:55-8:00 AKI Symposium - Plenary 1 Molecules, Mechanisms and Targets    Co-chair: Anupam Agarwal, MD    Co-chair: Joseph V. Bonventre, MD, PhD 7:55-8:00 Opening Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP 8:00-8:20 PW1 Energy Metabolism and Renal Stress Resistance Samir Parikh, MD 8:20-8:40 PW1 Sickle Cell Disease: Renal Manifestations and Mechanisms Karl Nath, MD 8:40-9:00 PW1 Epigenetic Changes in AKI-CKD Transition Masaomi Nangaku, MD, PhD 9:00-9:20 PW1 Hypoxia Energetics and Renal Hemodynamics Prabhleen Singh, MD 9:20-9:40 PW1 Function-blocking avb5 and avb6 Integrins Minimize Ischemic Kidney Injury Bruce A. Molitoris, MD 9:40-10:00 Discussion 10:00-10:15 Coffee Break 10:15-10:35 AKI Symposium - Plenary 2 Of Mice and Men: Harmonizing Human and Animal AKI    Co-chair: Bruce A. Molitoris, MD    Co-chair: Paul Sanders, MD 10:15-10:35 PW1 Sepsis Induced AKI: A Distinct Molecular Phenotype John A. Kellum, MD 10:35-10:55 PW1 Pericyte Biology and AKI/CKD Transition Ben Humphreys, MD, PhD 10:55-11:15 Drug Discovery to Halt the Progression of AKI to CKD Mark De Caestecker, MB BS, PhD 11:15-11:35 Human Kidney Organoids and Their Use in Modeling Diseases Joseph V. Bonventre, MD, PhD 11:35-11:55 Remote Effects of Acute Kidney Injury Matthieu LeGrand, MD, PhD 11:55-12:15 Discussion 12:15-1:15 Lunch Hosted by Conference for Workshop Participants 1:15-1:35 AKI Symposium - Plenary 3 Bench to Bedside: Translating Discoveries to Clinical Care    Co-chair: Claudio Ronco, MD    Co-chair: Mitchell H. Rosner, MD 1:15-1:35 Nonpharmacological - Biomechanical Approaches to Control Inflammation in AKI Mark D. Okusa, MD 1:35-1:55 Immune Cells in AKI and Repair Hamid Rabb, MD 1:55-2:15 Lymphocyte Function in Human AKI Marlies Ostermann, MD 2:15-2:35 Stem Cell-derived Microparticles in AKI Vincenzo Cantaluppi, MD 2:35-2:55 Vasopressin: A Novel Target for Prevention and Retardation of Kidney Disease Lise Bankir, PhD 2:55-3:15 Discussion 3:15-3:30 Coffee Break 3:30-3:50 AKI Symposium - Plenary 4 Controversies in AKI    Co-chair: Patrick T. Murray, MD    Co-chair: Marlies Ostermann, MD 3:30-3:50 AKI Adjudication: Do We Need It? Kathleen Liu, MD, PhD, MAS 3:50-4:10 Interventions to Prevent Peri-operative AKI Amit Garg, MD 4:10-4:30 The Economic Consequences of AKI Glenn Chertow, MD 4:30-4:50 Clinical Trial Endpoints in AKI: Report from the STEP Group Andrew D. Shaw, MB, FRCA, FFICM, FCC 4:50-5:10 Care of the AKI Survivor Ron Wald, MD 5:10-5:30 Discussion 5:30pm AKI Workshop Adjourns Practice Based Learning in CRRT: The Science and the Art Tuesday March 7 PW2 - Practice Based Learning in CRRT: The Science and the Art This workshop is designed to provide participants with the knowledge and understanding for decision making for the effective utilization of CRRT to manage critically ill patients. For the hands on Workshop Rotations all participants will be allocated to teams of 6 to 8 participants. The workshop will utilize case based discussions and "hands on" interactions with machines to illustrate the underlying concepts for application of CRRT. Delegates will participate in group exercises to apply their learning for the management of complex cases. At the end of this workshop participants will have an improved understanding of how to utilize CRRT for optimizing renal support. A quiz will be administered pre-and post- course for assessment. Learning Objectives: - Describe the underlying concepts and review the process of decision making for choice of CRRT therapy components and their implementation - Obtain hands on experience in machine set-up troubleshooting prescription and delivery - Utilize the tools provided to manage complex cases with CRRT. 7:45-8:00 Full Day Concurrent Workshop - PW2 7:45-8:00 PW2 Opening Remarks Jorge Cerda, MD, FACP, FASN Ashita Tolwani, MD 8:00-8:30 Pre-Course Test Jorge Cerda, MD, FACP, FASN Ashita Tolwani, MD 8:30-9:15 Patient Selection and Prescription on CRRT Jorge Cerda, MD, FACP, FASN 9:15-10:00 CRRT: The Technical Questions - Modality & Dose Ashita Tolwani, MD 10:00-10:15 Coffee Break 10:15-10:55 CRRT: The Technical Questions - Access Membrane Circuit Luis Juncos, MD 10:55-11:25 CRRT: Solutions & Fluid Management Nithin Karakala, MD 11:25-12:00 CRRT Outcome Studies: Survival and Renal Recovery Michael Connor, MD 12:00-1:00 Lunch Hosted by Conference for Workshop Participants 1:10-4:00 Hands-On Workshop Rotations - All Teams The hands-on sessions will use a case-based approach to provide training on different aspects of CRRT. All participants will be allocated to teams of 12 to 15 that will have nurses, pharmacists and physicians represented in each team. Each team will go through four interactive case discussions and role-playing with team members. The workshop is divided into four (4) sessions 35 minutes in length that will occur simultaneously. Each session will be repeated 4 times so teams can rotate through each session in order to maximize the learning opportunity. Teams rotate during 5 minute breaks between sessions. Pediatric teams will rotate only through the pediatric section. 1:10-4:00 SESSION 1 CRRT Prescription/Order Sets/Documentation Jorge Cerda, MD, FACP, FASN Patty Graham, RN, MS, CCRN, CS Operationalizing the prescription for different modalities; documentation 1:10-4:00 SESSION 2 Circuit Anticoagulation Citrate Protocols Teri Shell, RN Ashita Tolwani, MD Access and circuit setup, citrate anticoagulation, monitoring and adjustments 1:10-4:00 SESSION 3 CRRT Dose/Fluid/Drug Dosing Linda Awdishu, PharmD, MAS Michael Connor, MD Noel Oabel, BSN, RN, CNN Setting the machine for volume management, solute clearances and adjustments for drugs and nutritional support 1:10-4:00 SESSION 4 Monitoring Alarms and Connections with Other Therapies Luis Juncos, MD Nithin Karakala, MD Isagani Marquez, MSN, RN, QIA Brenda Stofan, RN Assessment and correction of alarm states and managing connections with ECMO/ECCOR and apheresis 1:10-4:00 PEDIACTRIC SESSION David Askenazi, MD, MSPH Stuart L. Goldstein, MD Theresa Mottes, BSN, RN, CDN Modality selection, circuit modifications, therapy dosing, monitoring, adjustments for targeted interventions 4:00-4:15 Coffee Break 4:15-4:55 Interactive Clinical Case (Decision Making) Ashita Tolwani, MD 5:00-5:30 Post Course Test and Wrap-up Jorge Cerda, MD, FACP, FASN Ashita Tolwani, MD 5:30pm Adjourn 5:30-7:30pm Reception and Poster Review For All Conference Attendees Glenn Chertow, MD Amit Garg, MD Samir Parikh, MD Hamid Rabb, MD Jordan M. Symons, MD Ravi Thadhani, MD ORAL POSTER SESSIONS: BASIC AND APPLIED RESEARCH IN AKI Parikh & Rabb (Moderators) CLINICAL RESEARCH IN AKI - I Thadani & Symons (Moderators) EPI AND OUTCOMES - I Chertow & Garg (Moderators) Wednesday, Morning March 8 7:00am-4:30pm Conference Registration Open 7:00-8:15 Meet the Experts 7:00-8:15 ME1 MEET THE EXPERT How I Assess Patients in the ICU and My Approach to Oliguria Glenn Chertow, MD John Louis Vincent, MD PhD 7:00-8:15 ME2 MEET THE EXPERT Getting Published: What Does It Take? Amit Garg, MD Karl Nath, MD Breakfast Symposia Breakfast Symposia Hosted by Conference (RSVP Required) Selection made during registration 7:00-8:15 A. Fluids and Vasopressor Management in the ICU Lakhmir S. Chawla, MD Michael Connor, MD Luis Juncos, MD Andrew D. Shaw, MB, FRCA, FFICM, FCC CME Available Juncos & Connor (Moderators) - Shaw, Chawla (Discussants) 7:00-8:15 B. Management of AKI in Sepsis: Are We Ready? Jacques Duranteau, MD Geoffrey Fleming, MD Matthieu LeGrand, MD, PhD Peter Pickkers, MD, PhD Miet Schetz, MD, PhD CME Available Schetz, Fleming (Moderators) Pathophysiology of AKI in Sepsis - Legrand Role of the Microcirculation in Sepsis - Duranteau Therapeutic Targets and Interventions - Pickkers SESSION I: PATIENT CHARACTERISTICS 8:20-8:30 Plenary 1 MINI-SYMPOSIA Organ Dysfunction in the Critically Ill Patient: Emerging Concepts    Co-chair: Miet Schetz, MD, PhD    Co-chair: Andrew D. Shaw, MB, FRCA, FFICM, FCC 8:20-8:30 Opening Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP 8:30-8:45 Pathophysiology of Heart Failure Alan Maisel, MD 8:45-9:00 What's New in ARDS? Kathleen Liu, MD, PhD, MAS 9:00-9:15 AKI in Trauma Patients Jacques Duranteau, MD 9:15-9:30 The Critically Ill Burn Patient Matthieu LeGrand, MD, PhD 9:30-9:45 Renal Dysfunction in Cirrhosis Mitra Nadim, MD 9:45-10:00 Personalized Medicine in Sepsis: Inhibition and Stimulation of the Immune System Peter Pickkers, MD, PhD 10:00-10:15 Shared Decision Making in the ICU Judy E. Davidson, DNP, RN, FCCM 10:15-10:30 Panel Discussion John A. Kellum, MD 10:30-11:00 Coffee Break STANDARD WORKSHOPS Open to all participants and applicable to physicians, nurses and allied personnel. Workshop Codes: C= Core workshop, I = Intermediate, A = Advanced, N= Nurses, AP = of interest to nurses and allied personnel Workshops presented in a series are marked with a "1" for a primary workshop discussion in this area and "2" for a more complex or advanced discussion in this area. Please note that the series workshops 1 and 2 can be either taken subsequently (following each other) or they can each be taken independently (e.g. workshop 1 can be taken without taking workshop 2 and vice versa). FOCUSED SYMPOSIA These focused symposia are offered in 3 categories (3 sessions in each category) on Wednesday and Thursday and run concurrrently with the Standard Workshops. Sessions can be taken as a group (3) or independently. Selections made during online registration process. 11:00-12:30 Standard Workshop Group 1 11:00-12:30 A01 Using Kidney Biomarkers for AKI 1: Risk Assessment, Diagnosis and Staging Rajit Basu, MD MMI Azra Bihorac, MD MS Patrick T. Murray, MD Practical issues for use of kidney biomarkers for assessing risk and for early recognition and interventions in AKI. 11:00-12:30 B02 Strategies for Optimizing the CRRT Circuit (Access, Anticoagulation and Monitoring) Citrate Anticoagulation David Askenazi, MD, MSPH Luis Juncos, MD Ron Wald, MD Case based discussions on best practices to maintain circuits for CRRT focusing on the Access, Anticoagulation and Monitoring. Citrate anticoagulation 11:00-12:30 C03 Using Electronic Medical Records and Big Data to Improve care in AKI Andrew Lewington, MD Scott Sutherland, MD Principles and strategies to access EMR and big data to track and manage patients at risk for and with AKI to improve outcomes. 11:00-12:30 D04 Managing Patients with AKI and Liver Failure 1: Pathophysiology, Differential Diagnosis, Therapy, Use of RRT, Liver Support, Strategies for Bridge to Transplant John A. Kellum, MD Mitra Nadim, MD Chirag Parikh, MD, PhD Pathophysiology of AKI in setting of acute and chronic hepatic failure and management strategies for differential diagnosis and therapy. 11:00-12:30 E05 Assessment of Fluid Responsiveness, Hemodynamic Monitoring and Targets Jacques Duranteau, MD Andrew D. Shaw, MB, FRCA, FFICM, FCC Principles and strategies for volume assessment, hemodynamic and microcirculatory monitoring in critically ill patients. 11:00-12:30 F06 Improving AKI Care in the Developing World Emmanuel Burdmann, MD, PhD Jorge Cerda, MD, FACP, FASN Etienne Macedo, MD, PhD Practical issues for recognition and optimal management of patients with AKI in resource poor settings applying the lessons learned from the ISN 0by25 initiative. 11:00-12:30 G07 Principles of Plasma Exchange, Applications and Practical Issues Eisei Noiri, MD., PhD. Amber Sanchez, MD Sarek Shen Rationale and technique of plasma exchange and its applications, case based discussions. Lunch Symposia Lunch Symposia Hosted by Conference (RSVP Required) Selection made during registration 12:30-2:00 W1. Measuring Renal Function: Which Biomarkers? Noel Gibney, MB FRCP(C) Alan Maisel, MD Bruce A. Molitoris, MD Peter Pickkers, MD, PhD John Prowle, MA MSc MD FRCP FFICM Non-CME Available Moderators: Maisel and Gibney Pro-enkephalin - Pickkers Cystatin C and Creatinine - Prowle Real Time GFR - Molitoris 12:30-2:00 W2. Fluid Management of the Critically Ill Patient: Crystalloids, Colloids and Blood Products Michael Connor, MD Kathleen Liu, MD, PhD, MAS Miet Schetz, MD, PhD Andrew D. Shaw, MB, FRCA, FFICM, FCC John Louis Vincent, MD PhD CME Available Moderators: Connor and Liu Discussants: Vincent, Schetz and Shaw 12:30-2:00 W3. Extracorporeal Support for Multiorgan Failure: Emerging Strategies David Askenazi, MD, MSPH Patrick M. Honore, MD, PhD John A. Kellum, MD Claudio Ronco, MD Jordan M. Symons, MD CME Available Moderators: Honore and Symons Sorbents from Bench to Bedside - Ronco ECMO and CRRT - Askenazi Sorbent Based Therapy - Kellum 12:30-2:00 W4. Establishing and Maintaining Core Competencies for Nurses for CRRT Linda Awdishu, PharmD, MAS Judy E. Davidson, DNP, RN, FCCM Patty Graham, RN, MS, CCRN, CS Eileen Lischer, MA, BSN, RN, CNN Theresa Mottes, BSN, RN, CDN CME Available Moderators: Awdishu and Davidson Discussants: Lischer, Mottes and Graham Wednesday, Afternoon, March 8 2:00-3:30 Standard Workshop Group 2 2:00-3:30 A08 Using Kidney Biomarkers for AKI 2: Differential Diagnosis, Interventions and Prognosis Stuart L. Goldstein, MD Patrick T. Murray, MD Eisei Noiri, MD., PhD. Strategies for the effective use of kidney biomarkers for managing patients with AKI to guide interventions and predict outcomes. 2:00-3:30 B09 CRRT for the Experienced User 1 Rolando Claure-Del Granado, MD, FASN Claudio Ronco, MD Interactive case based discussions on dose adjustments, monitoring for adequacy, modality selection and transitions in CRRT. 2:00-3:30 C10 Starting and Stopping RRT for AKI: Principles and Practice Etienne Macedo, MD, PhD Ravindra L. Mehta, MBBS, MD, DM, FACP Principles of determining when to start and stop RRT. Case based discussion of various approaches. 2:00-3:30 D11 Managing Patients with Sepsis 1 : Pathophysiology, Diagnosis, Assessment, Resuscitation, Drug Management, Techniques for Disease Modification, Organ Support and Renal Protection Geoffrey Fleming, MD Patrick M. Honore, MD, PhD John Louis Vincent, MD PhD Case based discussions on pathophysiology of sepsis, rationale and strategies for fluid and vasopressor use for supportive therapy with the sepsis bundle. Technical considerations and practical application of extracorporeal support techniques for sepsis. Results of human studies for use of high permeability membranes, HVHF, VHVHF and hybrid techniques for sepsis. 2:00-3:30 E12 Fluids and Solutions in AKI Management: Crystalloids, Colloids and Blood Products - When and How to Use Xiaoquiang Ding, Prof John A. Kellum, MD Andrew D. Shaw, MB, FRCA, FFICM, FCC Techniques, applications, monitoring and practical issues for implementation. 2:00-3:30 F13 Pediatric AKI and CRRT: How do I Care for My Patient and My Program? David Askenazi, MD, MSPH Theresa Mottes, BSN, RN, CDN Scott Sutherland, MD Review and discussion of best practices to develop your pediatric AKI and CRRT program, identify and treat your young patients with AKI, and to assure delivery of high-quality care in the pediatric setting. 2:00-3:30 G14 Practical Issues in Plasmapheresis: Setup and Troubleshooting, Combined CRRT with Apheresis Isagani Marquez, MSN, RN, QIA Noel Oabel, BSN, RN, CNN Amber Sanchez, MD Technique adaptations for combining CRRT with other extracorporeal support therapies. Circuit set up, logistics, monitoring and assuring safety. 3:30-4:00 Coffee Break 4:00-4:15 Plenary 2 MINI-SYMPOSIA Acute Kidney Injury (AKI): Pathophysiology    Co-chair: John Prowle, MA MSc MD FRCP FFICM    Co-chair: Mitchell H. Rosner, MD 4:00-4:15 Preeclampsia: Pathophysiology and Novel Therapeutic Options Ravi Thadhani, MD 4:15-4:30 Immunoregulatory Role of Tissue Microenvironment in Kidney Injury Mark D. Okusa, MD 4:30-4:45 Cell Cycle and DNA Repair in AKI to CKD Transition Joseph V. Bonventre, MD, PhD 4:45-5:00 AKI in Kidney Transplantation Hamid Rabb, MD 5:00-5:15 Renal Venous Congestion: The Unrecognized Culprit? Matthieu LeGrand, MD, PhD 5:15-5:30 Does Urine Output Monitoring Improve Outcome? John A. Kellum, MD 5:30-6:00 Special Lecture New Advances in the Treatment of Severe Sepsis and Septic Shock John Louis Vincent, MD PhD 6:00 Adjourn 6:00-8:00 6:00-8:00 Exhibit Reception and Poster Session Steven R. Alexander, MD Rajit Basu, MD MMI Emmanuel Burdmann, MD, PhD Michael Connor, MD Noel Gibney, MB FRCP(C) Eisei Noiri, MD., PhD. ORAL POSTER SESSIONS: CLINICAL RESEARCH IN AKI AND NAP - II Alexander & Gibney (Moderators) EPI AND OUTCOMES - II Burdmann & Connor (Moderators) NEW TECHNOLOGY RRT RESEARCH Noiri & Basu (Moderators) Thursday, Morning, March 9 7:00am-4:30pm Registration Open 7:00-8:00 Coffee Served 7:00-8:15 ME3 MEET THE EXPERT How I Use the KDIGO AKI Guidelines to Manage Patients John A. Kellum, MD Claudio Ronco, MD 7:00-8:15 ME4 MEET THE EXPERT Forget the Evidence: When Do I Start CRRT? Lui Forni, MD Kathleen Liu, MD, PhD, MAS Breakfast Symposia Breakfast Symposia Hosted by Conference (RSVP Required) Selection made during registration 7:00-8:15 C. Innovations in Caring for Patients with Hyponatremia Lise Bankir, PhD Michael Connor, MD Geoffrey Fleming, MD Mitchell H. Rosner, MD CME Available Fleming and Bankir (Moderators) Rosner and Connor (Discussants) This symposium will cover the pathophysiology of hyponatremia and discuss the practical issues for management of these disorders with novel agents using urea. 7:00-8:15 D. Measuring Outcomes in AKI and CRRT: Which Benchmarks Should We Use? Stuart L. Goldstein, MD Etienne Macedo, MD, PhD Marlies Ostermann, MD Ashita Tolwani, MD Ron Wald, MD CME Available Ostermann and Tolwani (Moderators) Wald, Goldstein and Macedo (Discussants) 8:15-9:45 Standard Workshop Group 3 8:15-9:45 A15 Preventing AKI: From Surveillance to Intervention Kianoush Kashani, MD Andrew Lewington, MD Richard Solomon, MD This workshop will describe the current status of methods to identify patients at high risk for AKI and techniques for electronic surveillance. Strategies and tools for preventing AKI in different settings will be discussed. 8:15-9:45 B16 CRRT for the Experienced User 2: Solutions, Fluid Removal Fluid Balance, Monitoring Ravindra L. Mehta, MBBS, MD, DM, FACP John Prowle, MA MSc MD FRCP FFICM Interactive case based discussion on strategies for fluid management in CRRT to achieve patient driven outcomes for fluid, electrolyte and acid base balance. 8:15-9:45 C17 Drug Induced Kidney Injury in the ICU: Mechanisms, Susceptibility, Diagnosis, Management Strategies Linda Awdishu, PharmD, MAS Stuart L. Goldstein, MD Miet Schetz, MD, PhD Causes and consequences of drug induced nephrotoxicity, factors contributing to toxicity, strategies for preventing and managing toxicity. Drug dosing during dialysis techniques. 8:15-9:45 D18 Managing Heart Failure and Cardio-Renal Syndrome: Pathophysiology, Diagnosis, Drug Management, Ultrafiltration, Renal Support and RRT for Patients with Ventricular Assist Devices and Artificial Hearts Luis Juncos, MD Claudio Ronco, MD Technical considerations, practical application and results of different methods to treat heart failure and cardio-renal syndrome including ultrafiltration techniques. 8:15-9:45 E19 Recognition and Management of Drug Intoxications Richard F Clark, MD Lui Forni, MD Ron Wald, MD Identification of different street drugs and other toxic substances contributing to AKI and principles and application of extracorporeal support techniques for management. 8:15-9:45 F20 Clinical Application of CRRT for Infants and Children Geoffrey Fleming, MD Daryl Ingram, RN, BSN, CDN Jordan M. Symons, MD Review and discussion of CRRT for pediatric patients, with emphasis on the specific challenges seen in children of all ages. Clinical cases will serve as the basis for discussion of technique, prescription, and outcome. This will be an interactive session - registrants are encouraged to send cases to the conference organizers for review and possible selection for 8:15-9:45 G21 Sorbent Based and Hybrid Therapies for Extracorporeal Support Xiaoquiang Ding, Prof Patrick M. Honore, MD, PhD Hemopurification systems for sepsis, immunoadsoprtion and PMMA. 9:45-10:00 Coffee Break SESSION II: CONTROVERSIES IN CRITICAL CARE NEPHROLOGY 10:00-10:15 Plenary 3 MINI-SYMPOSIA Challenges in ICU Management    Co-chair: Geoffrey Fleming, MD    Co-chair: Marlies Ostermann, MD 10:00-10:15 The 10 Elements that Can Improve Outcomes in Sepsis John Louis Vincent, MD PhD 10:15-10:30 Lactate: Good or Bad Guy? Lui Forni, MD 10:30-10:45 Neonatal AKI - Data from the International AWAKEN Study David Askenazi, MD, MSPH 10:45-11:00 We Should Measure Fluid Deficiency Not Fluid Responsiveness Andrew D. Shaw, MB, FRCA, FFICM, FCC 11:00-11:15 Evaluating Muscle Mass Using Markers of Kidney Function: Sarcopenia Index Kianoush Kashani, MD 11:15-11:30 AKI in the Patient with Cancer Mitchell H. Rosner, MD 11:30-12:00 SPECIAL LECTURE Translating to Management Award Clinical Applications of Biomarkers in AKI: Lessons from the TRIBE-AKI Studies Chirag Parikh, MD, PhD 12:00-12:15 Top Abstract Awards Lunch Symposia Lunch Symposia Hosted by Conference (RSVP Required) Selection made during registration 12:15-1:45 T1. Biomarker Guided Management of AKI: Strategies for Improving Care Azra Bihorac, MD MS Lakhmir S. Chawla, MD Kianoush Kashani, MD John A. Kellum, MD Alex Zarbock, MD CME Available Moderators: Chawla and Kellum Discussants: Zarbock Kashani and Bihorac 12:15-1:45 T2. Hydration and Kidney Health Emmanuel Burdmann, MD, PhD Rajasekara Chakravarthi, MD, DNB (Nephrology) William Clark, MD Matthieu LeGrand, MD, PhD Andrew Lewington, MD CME Available Moderators: Chakaravarthi and Lewington Pathophysiology of Water Handling by the Kidney - LeGrand The Role of Dehydration in AKI - Burdmann Hydration Status and Kidney Disease: What is the Evidence - W. Clark 12:15-1:45 T3. Imaging Modalities for Patients with AKI and CKD Steven R. Alexander, MD Jacques Duranteau, MD John Prowle, MA MSc MD FRCP FFICM Miet Schetz, MD, PhD Richard Solomon, MD CME Available Moderators: Alexander and Schetz Discussants: Duranteau, Prowle and Solomon 12:15-1:45 T4. Therapeutic Challenges in AKI and CKD: Managing Acid Base and Electrolyte Problems Luis Juncos, MD Patrick T. Murray, MD Chirag Parikh, MD, PhD Mitchell H. Rosner, MD James A. Tumlin, MD CME Available Moderators: Murray, Parikh Discussants: Rosner, Juncos, Tumlin 12:15-1:45 I1. Additional Industry Session Offered (non-CME) More Information SESSION III: EMERGING CONCEPTS IN AKI AND RRT 1:45-2:00 Plenary 4 MINI SYMPOSIA Novel Strategies in AKI Management    Co-chair: Andrew Lewington, MD    Co-chair: Eisei Noiri, MD., PhD. 1:45-2:00 Population-Based Studies of Drug Induced Acute Kidney Injury Amit Garg, MD 2:00-2:15 Acute Interstitial Nephritis: An Update 2:15-2:30 Real Time Measurement of GFR Using an Optical Transdermal Fluorescence System Richard Solomon, MD 2:30-2:45 Current and Potential Role of Point-of-care Ultrasound in Acute Kidney Injury Jacques Duranteau, MD 2:45-3:00 From Tea Leaves to Intelligent Systems: Forecasting Risk for AKI Azra Bihorac, MD MS 3:00-3:15 AWARE - Operationalizing The Renal Angina Index and Biomarkers to Predict Severe AKI Stuart L. Goldstein, MD 3:15-3:30 Biomarkers of Drug-induced Kidney Injury: Findings of the SAFE-T Consortium Patrick T. Murray, MD 3:30-4:00 Coffee Break 4:00-4:15 Plenary 5 MINI SYMPOSIA Challenges and Controversies in Renal Support and CRRT    Co-chair: Stuart L. Goldstein, MD    Co-chair: Ashita Tolwani, MD 4:00-4:15 Renal Support During Liver Transplantation Mitra Nadim, MD 4:15-4:30 Blood Purification for Sepsis Patients Based on the Current Pathophysiology of Sepsis Patrick M. Honore, MD, PhD 4:30-4:45 Nutrient Deficiency in AKI and Losses During CRRT Marlies Ostermann, MD 4:45-5:00 Serum Creatinine Variability: A Renal Vital Sign? Lakhmir S. Chawla, MD 5:00-5:30 Special Lecture Precision CRRT: Results from ADQI 17 Claudio Ronco, MD 5:30-6:00 Viewpoints: Timing of RRT in AKI Glenn Chertow, MD James A. Tumlin, MD Ron Wald, MD Alex Zarbock, MD We Know When to Start - Zarbock We Are Still Trying to Find Out - Wald We Are a Long Ways Off - Chertow Moderator - Tumlin 6:00 Adjourn Free Evening Friday, Morning, March 10 7:00am-1:00pm Conference Registration Open 6:45-8:00 6:45-8:00 I2. Additional Industry Breakfast Session Offered (RSVP Required - non-CME) Selection made during registration More Information 7:30-8:00 Coffee Served SESSION IV: IMPROVING OUTCOMES IN AKI 8:00-8:15 Plenary 6 MINI SYMPOSIA Global Burden of AKI    Co-chair: Emmanuel Burdmann, MD, PhD    Co-chair: Jorge Cerda, MD, FACP, FASN 8:00-8:15 Population Based Study of AKI Epidemiology Kianoush Kashani, MD 8:15-8:30 The DoRemi Trial Claudio Ronco, MD 8:30-8:45 Optimal Circumstances and Utilization of RRT in Older Critically Ill Patients including presenting the results of the OPTIMAL-AKI Study Azra Bihorac, MD MS 8:45-9:00 AKI in the ICU: The Intensive Care Over Nations (ICON) Audit Peter Pickkers, MD, PhD 9:00-9:15 Pattern and Outcome of AKI in Tertiary Care Hospital in India Sanjay Agarwal, MD 9:15-9:30 Education and Training to Raise Awareness of AKI in the Community Andrew Lewington, MD 9:30-9:45 The ISN 0by25 AKI Pilot Study: What Have We Learnt? Ravindra L. Mehta, MBBS, MD, DM, FACP 9:45-10:00 Community Acquired AKI in Resource Constrained Settings: Risk Assessment and Management Etienne Macedo, MD, PhD 10:00-10:30 SPECIAL LECTURE Management of AKI in the Developing World: Highlights from ADQI 18 Rajasekara Chakravarthi, MD, DNB (Nephrology) 10:30-11:00 Coffee Break SESSION V: FUTURE TRENDS IN CRRT AND CRITICAL CARE 11:00-11:15 Plenary 7 MINI SYMPOSIA Emerging Strategies in AKI and Extracorporeal Support    Co-chair: Xiaoquiang Ding, Prof    Co-chair: Patrick M. Honore, MD, PhD 11:00-11:15 Drug Induced Nephrotoxicity: Findings from the DIRECT Study Linda Awdishu, PharmD, MAS 11:15-12:30 Update from Ongoing and Late Breaking Trials (12 minutes each) Amit Garg, MD Kathleen Liu, MD, PhD, MAS Peter Pickkers, MD, PhD Alex Zarbock, MD 1. Large Randomized Controlled Trials of Interventions to Prevent Peri-operative AKI - Garg 2. Alkaline Phosphatase for Septic AKI - Pickkers< 3. STAART AKI Trial Update - Lui 4. Prevention of Cardiac Surgery Associated AKI: The Prev AKI Trial - Zarbock 12:30-12:55 Critical Care Nephrology: Literature Review Noel Gibney, MB FRCP(C) 12:55-1:00 Closing Remarks Ravindra L. Mehta, MBBS, MD, DM, FACP 1:00 Conference Adjourns